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Ancient DNA Analysis
Analysis of ancient DNA (aDNA) is new powerful means to study biological excavation specimens and answer paleontological and archaeological science questions.
Comprehensive genome sequencing of genetic material, salvaged into ancient biological specimens (bones and teeth of human and animals, seeds, wood, food residues etc.), can shed light into various anthropological and historical events related to the human origin, the migrations of populations, the domestication of species, the identity and appearance of individuals, diet information, genetic diseases and pathogens.
The workshop will cover:
- Demonstration and discussion about the conditions and sampling procedure of ancient biological residues in the field, introduction to wet-lab procedures (lab precautions, sample handling, DNA extraction, genomic libraries preparation, sequencing etc).
- Process of ancient DNA data (Next Generation Sequencing data handling and filtering, DNA damage estimation, contamination check, comparison to reference data).
- Utilization of ancient DNA data to species identification analysis.
- Determination of morphological characteristics of individuals (e.g. color, shape) and genetic sex estimation.
- Introduction to population genetics studies focusing on origin, migration patterns and genetic admixture among populations.